Insulin discovery a game-changer for improving diabetes treatments

An international collaboration co-led by researchers at the Walter and Eliza Hall Institute has made a discovery that could enable therapeutic insulins to be made more effective than they currently are.

The findings will help to improve treatments for diabetes, a disease that impacts the lives of millions of people worldwide.

Published in Nature Communications, the study reveals the first definitive 3D image of how insulin successfully interacts with its receptor, a ‘gatekeeper’ for transmitting information into cells, in a process that is crucial for instructing cells to lower blood sugar levels in the body.

Understanding exactly what this process looks like can inform the design of faster-acting and longer-lasting insulin therapies.

Type 2 diabetes is a commonly found chronic disease caused due to improper production or utilization of insulin. Chances for getting type 2 diabetes to vary from person to person. Heredity, hypertension and old age are the main risk factors for type 2 diabetes. It may cause several negative impacts on life like increased appetite, increased thirst, blurred vision, fatigue, and erectile dysfunction. After evaluating symptoms, you can easily verify this disorder by conducting blood tests. Fasting blood glucose level, oral glucose tolerance level, and hemoglobin A1c test are some of the best-recommended blood tests for verifying type 2 diabetes. Even though diabetes is not fully curable, we can maintain the normal level of blood sugar level in the body by following a healthy lifestyle with proper medications. Now let’s see in detail some of the best diabetes treatment for type 2. Intake of oral medicines is a commonly prescribed diabetes treatment for type 2 helping in maintaining a balanced blood sugar level. At present, there are many oral medicines available at medical stores. Before using oral medicines, it is advised to seek guidance from a physician for knowing your correct dosage level. Sulphonylureas is one among the best used oral diabetic medicines promoting insulin production in the pancreas. The release of insulin from beta cells lowers the amount of blood sugar level and reduces the risk of the hyperglycemic condition. You can also intake sulphonylureas with metmorphin for treating type 2 diabetes. Intake of metmorphin reduce the amount of sugar absorbed by intestinal walls, make body cells more sensitive to insulin action and limits the release the glucose from liver to bloodstream. It is a perfect solution for those who are suffering from type 2 diabetes due to overweight problems. Acarbose, exenatide, glitazones, and gliptins are other common oral medicines suggested` for the treatment of type 2 diabetes. Following a healthy diabetic diet is a best-recommended type 2 diabetes treatment. A diabetic diet is a blend of nutritive, low caloric value and low cholesterol level food items. Green leafy vegetables, fresh fruits, nuts, brown rice, millet, pearled barley, and quinoa are the main food items included in the diabetic diet. While following a diabetic diet, it is advised to intake frequent light meals instead of heavy meals. Potatoes, ghee products, spices, and oily fried food items should be avoided. It is also advised to cease the intake of alcohol and processed food items for maintaining a balanced blood sugar level. Proper exercise is another suggested diabetes treatment for lowering blood sugar level. Doing regular exercises helps in proper functioning of metabolic activities and lowers heightening of blood sugar level. Performing aerobic exercises like walking, jogging, bicycling and swimming helps in promoting overall well being of the person. It reduces overweight, prevents heart diseases, reduces hypertension problems and improves muscle sensitivity towards insulin. Practicing of yoga exercises is another effective type 2 diabetes treatment used for stimulating the functioning of the pancreas. Bhramari, Surya namaskar, sabha asana, and pavanamukta asana are some among the best recommended yogic exercises for the treatment of type 2 diabetes. Source: Free Articles from

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